Influence of SLCO1B1 in gastric cancer patients treated with EOF chemotherapy
نویسندگان
چکیده
منابع مشابه
Chemotherapy in Elderly Patients with Gastric Cancer
Gastric cancer (GC) is one of the most frequent malignant diseases in the elderly. Systemic chemotherapy showed an improvement of quality of life and survival benefit compared to supportive care alone in patients with advanced GC. Because comorbidities or age-related changes in pharmacokinetics and pharmacodynamics may lead to higher toxicity, however, many oncologists hesitate to recommend eld...
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PURPOSE Wnt pathways control key biological processes that potentially impact on tumor progression and patient survival. The present study analyzed the polymorphism of lipoprotein-related receptor 5 (LRP5) (gene with key functions in Wnt signaling) and its impact on the response to chemotherapy and survival of patients with advanced gastric cancer (AGC). METHODS A total of 107 consecutive pat...
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Background: The optimal nodal staging scheme for gastric cancer remains unsettled. We compared the prognostic performances of the metastatic lymph node, lymph node ratio, and log odds of metastatic lymph nodes based on nomograms among 801 patients with D2-resected gastric cancer treated with adjuvant chemotherapy. Methods: When assessed as a continuous covariate, each nodal staging variable was...
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Experimental evidence suggests that probiotics might have beneficial effect on the toxicity of anticancer therapy. In this study, the Double Blind Clinical trial was used to collect information and data. Participants were randomly divided into two experimental groups (probiotic) and a control group (placebo) after obtaining the consent of the company. At the start of the study, during a meeting...
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ژورنال
عنوان ژورنال: Oncology Letters
سال: 2018
ISSN: 1792-1074,1792-1082
DOI: 10.3892/ol.2018.9147